Optical filter option to improve measurements with fluorescent sample.Alternative laser, 50mW at 532nm for samples incompatible with the standard 633nm laser.Optional flow mode capability to enable use as a GPC / SEC size detector.Automation of measurements using an autotitrator option.
Zeta potential using patented M3-PALS technology.Our regular eNews including the latest news, education, events and offers from Malvern Panalytical. Size measurement from 0.3nm (diameter) to 10 microns using patented NIBS (Non-Invasive Back Scatter) technology. Application notes, technical notes, articles, white papers and software downloads.In addition, a microrheology option is available for measuring sample viscosity and viscoelastic properties, as well as a Protein Measurement option for protein mobility measurements. The calculation of zeta potential from the measured electrophoretiic. Using Non-Invasive Backscatter optics (NIBS) it has significantly better performance than systems using 90 degree scattering optics. Just to add that similar arguments apply when using the Zetasizer for electrophoresis. The ZSP also incorporates a zeta potential analyzer that uses electrophoretic light scattering for particles, molecules and surfaces, and a molecular weight analyzer using static light scattering. The Zetasizer Nano ZS is a high performance two angle particle and molecular size analyzer for the enhanced detection of aggregates and measurement of small or dilute samples, and samples at very low or high concentration using dynamic light scattering with ‘NIBS’ optics. It is used for the measurement of the size, electrophoretic mobility of proteins, zeta potential of colloids and nanoparticles, and optionally the measurement of protein mobility and microrheology of protein and polymer solutions. The concentration of virus nanoparticles can be calculated based on the two measured scattered light intensities by knowing the refractive index of the dispersing solution, of the polymer and virus nanoparticles as well as their relative sphere equivalent diameters.Zetasizer Nano ZS for size, zeta potential, protein mobility and microrheology - Performance, simplicity, versatility. Measuring the intensity of the light scattered by polymeric nanoparticles of known concentration and comparable size with the investigated virus particle. Measuring the intensity of the light scattered by viruses suspended in an aqueous solution. The method is especially relevant for preparation of virus particle concentration standards and to vaccine formulations based on attenuated or inactivated virus particles where the classical plaque forming assays cannot be applied. Further limitations may arise if the refractive index of the virus is unavailable or cannot be calculated based on its composition, such as in case of enveloped viruses. 1/10th of the wavelength of the scattered monochromatic light (∼70 nm diameter). The method is applicable for virus particles acting as Rayleigh scatterers, i.e., virus particles with equivalent diameters up to ca. The suitable parameters (viscosity, absorption and refractive index) were chosen for each ZnO and dispersants. Size distributions of the nanoparticles were determined with a Malvern Zetasizer Nano ZS (Malvern Instruments Ltd., GB) by the DLS technique. Instead, as standards, well-characterized polymeric nanoparticle solutions are used. Samples were again sonicated for 5 minutes. As such, it became necessary to determine if RI could detect smaller changes in slurry composition and, therefore, provide a tighter control. We have adapted a static light scattering based method for the quantification of virus particles (shown for poliovirus) without the need of virus particle standards. We investigated the possibility of employing refractive index (RI) measurements for inline incoming slurry control at the point of use (POU), as an alternative to the widespread densitometry method. Most often the determination of the concentration of virus particles is rendered difficult by the availability of proper standards.